• This study provides an innovative model to harness

  2019-06-26

  

  This study provides an innovative model to harness national household survey data to quantify the effects of the various malaria control interventions. The model accounts for the spatial dependence in parasitaemia as a consequence of the heterogeneous distribution of malaria transmission and its dri

• Teriflunomide The very fact that providing a

  2019-06-26

  

  The very fact that providing a greater number of doses of IPTp-SP is incrementally effective, even in settings where the parasite is sensitive, also highlights the potential benefit of interventions using more effective drugs. This finding means there is either scope to improve clearance of existing

• It is established that hypoxia can induce autophagy

  2019-06-25

  

  It is established that hypoxia can induce autophagy [32,34–37]. We evidenced the autophagic activation in the cultured human osteosarcoma MG-63 Bax inhibitor peptide P5 after incubation in 1% O2 for 24h. The concomitantly elevated LC3 protein levels with HIF-1α high expression on OS tissue sections

• The congruence between BrS and ERS

  2019-06-25

  

  The congruence between BrS and ERS with respect to clinical manifestations and response to therapy lends further support to the repolarization hypothesis. Using an experimental model of ERS, Koncz et al. [30]. recently provided evidence in support of the hypothesis that, similar to the mechanism ope

• Cholangiopathies are a group of rare

  2019-06-25

  

  Cholangiopathies are a group of rare diseases whose primary or secondary target is the cholangiocyte. The onset and subsequent development processes of cholangiopathies are extremely diverse, with causes that are genetic, neoplastic, immune-mediated, idiopathic, infectious, and toxin- or drug-induce

• The National Family Health Survey of India emphasises

  2019-06-25

  

  The National Family Health Survey of India emphasises the need to hydrate children who have diarrhoea, but there is no evidence to show that such an intervention in the home setting improves mortality. The eight out of ten practitioners who are unaware of childhood pneumonia symptoms in the developi

• During our analysis we sought to uncover the source

  2019-06-25

  

  During our analysis, we sought to uncover the source of the oft-cited so-called fact that the risk of maternal mortality of women aged 15–19 years is twice that of women aged 20–24 years (and that the risk for those younger than 15 years is five-times higher). We identified dozens of instances over

• br Drug resistant tuberculosis threatens

  2019-06-25

  

  Drug-resistant tuberculosis threatens to undermine advances in tuberculosis control worldwide. Multidrug-resistant tuberculosis (MDRTB), defined as resistance to isoniazid and rifampicin, requires treatment for up to 24 months with expensive diagnostics and second-line drugs. Fewer than 15% of pat

• Remote monitoring offers ongoing opportunities for managemen

  2019-06-25

  

  Remote monitoring offers ongoing opportunities for management from three perspectives: Concept of remote monitoring for PPY A failure Most HF-related hospitalizations are due to fluid accumulation, and careful surveillance of a patient\'s fluid status and symptoms is important [20]. To effectiv

• Performing an ajmaline test in

  2019-06-25

  

  Performing an ajmaline test in children is problematic for 2 reasons. First, the test is apparently less sensitive in children than in adults. In fact, in 1 study, a repeat ajmaline challenge performed after puberty unmasked BrS in 23% of relatives with a previously negative drug test performed duri

• There are important methodological issues affecting the stud

  2019-06-25

  

  There are important methodological issues affecting the study of child mortality inequalities on the basis of survey data. McKinnon and colleagues relied on rigorous analytical tools to study these changes, and in some aspects—for example the graphical display of the statistical significance of chan

• br The slow progress in endemicity mapping of neglected

  2019-06-25

  

  The slow progress in endemicity mapping of neglected tropical diseases (NTDs) in Africa and scaling up of mass drug administration (MDA) in all endemic countries has hampered efforts to meet the London 2020 elimination and control targets. Lymphatic filariasis is targeted to be eliminated by 2020

• Accurate identification of FAS prevalence is challenging bec

  2019-06-25

  

  Accurate identification of FAS prevalence is challenging because of the global use of several different diagnostic criteria; different methods of case ascertainment; low confidence of health professionals making the diagnosis; and little access to normative data (eg, for assessment of sentinel facia

• Por otro lado el proceso de negociaciones que llevan a

  2019-06-24

  

  Por otro lado, el proceso de negociaciones que llevan cell cycle regulation cabo ambos gobiernos, demuestra, según estudiosos estadounidenses, que hay un reconocimiento de parte de los funcionarios de Estados Unidos, de que Cuba está ayudando a poner fin a la insurgencia de las farc en Colombia, que

• Diagnosis of pituitary metastasis could

  2019-06-24

  

  Diagnosis of pituitary metastasis could be missed by medical practitioners because most patients who developed pituitary metastasis are clinically asymptomatic. Patients may have signs and symptoms of nausea, vomiting, fatigue, and weight loss, which could also be viewed as pan-hypopituitarism, and

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