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VSV-G Peptide synthesis Plasma apelin levels predict the maj
2024-04-22
Plasma apelin levels predict the major cardiovascular event after percutaneous coronary intervention in patients with ST elevation myocardial infarction (STEMI), and adverse events are higher in patients with lower plasma apelin levels [75]. Apelin and its receptor are markedly upregulated in the he
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APJ receptor expression is altered
2024-04-22
APJ receptor expression is altered in various cardiovascular diseases, and both increases as well as decreases in APJ receptor expression have been reported. A decrease in mRNA and protein levels of APJ receptors was observed in patients with ischemic heart disease or idiopathic dilated cardiomyopat
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Second the choice of the PAABD is critical for
2024-04-22
Second, the choice of the PAABD is critical for an efficient and sensitive biosensor. The sequence of the PAABD should present high affinity and efficient recognition of the phosphorylated substrate, as opposed to poor affinity for the unphosphorylated substrate, and should display a fully reversibl
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br The prevalence of diabetes is increasing
2024-04-22
The prevalence of diabetes is increasing globally, and the situation is particularly alarming in Asia. The prevalence of diabetes in China has increased dramatically, from around 1% in 1980 to the most recent estimate of 9.7% according to a nationwide survey . Cumulative evidence shows that type 2
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br Materials and methods br Results br Discussion Several ma
2024-04-22
Materials and methods Results Discussion Several major signaling and developmental pathways (e.g. EGFR, ALK, KRAS, TGFβ, Notch and Wnt/β-catenin) have been shown to be involved in lung carcinogenesis and they are being exploited as targets of the non-small cell lung cancer therapy (for revi
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The Cebu Longitudinal Health and Nutrition Survey CLHNS geno
2024-04-19
The Cebu Longitudinal Health and Nutrition Survey (CLHNS) genome-wide association study investigated the genetic loci associated with plasma adiponectin in 1776 unrelated Filipino women. Adiponectin was strongly associated with three genetic positions: the gene CDH13 (rs3865188, P ≤ 7.2 × 10−16), ne
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Tension within the network could be
2024-04-19
Tension within the network could be explained by two potential mechanisms: the more classical contractility that is dependent on motor proteins that are pulling Celecoxib filaments towards each other [10]; or contractility that is caused by disassembly of a crosslinked network of actin filaments [2]
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Princen Panier specifically address the issue
2024-04-19
Princen, 2012, Panier, 2013 specifically address the issue of ACE using the commercial database AMADEUS. However, both studies focus only on corporate leverage and the ACE in Belgium. Due to the lack of a counterfactual, these authors consider firms in other European countries, e.g., France, as a co
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It has been reported that leukotrienes and
2024-04-19
It has been reported that leukotrienes and their receptors, e.g. the cysteinyl leukotriene receptor 1 (CysLT1) may promote sphingosine injury (Ding et al., 2007) and that increased 5-LOX expression and activity lead to production of brain-toxic molecules (Khan et al., 2010). However, differential ef
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A previous study reported that the
2024-04-19
A previous study reported that the serotonergic mechanism was involved in the psychological stress-induced alteration in synaptic plasticity in the rat hippocampal CA1 field (Matsumoto et al., 2004). Sumitaka Inoue et al. (Inoue et al., 2014) reported that pretreatment with a 5-HT1A receptor partial
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Given that neither case is derived from multiplex families
2024-04-19
Given that neither case is derived from multiplex Amyloid β-Peptide (1-42) with affected individuals, principles of Mendelian segregation cannot be applied to implicate the T201S mutation in causing familial CJD. In addition, like many rare gene variants, it is not possible to apply practice guideli
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br Identification of the croaker
2024-04-18
Identification of the croaker mAR cDNA Testosterone (T) was observed to alter steroidogenesis through a nongenomic mechanism (not blocked by the transcription inhibitor, actinomycin D) in Atlantic croaker ovarian tissues (Braun and Thomas, 2003). This action of T was mimicked by T conjugated to B
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p38 inhibitor Consistent with the in vitro results memantine
2024-04-18
Consistent with the in vitro results, memantine ameliorated Aβ-induced cytotoxicity in rat primary cortical cultures. Studies reported that memantine protected neurons against the damage caused by aggregated Aβ40 or Aβ42 oligomers in vivo[26], [27]. These results suggest that, in addition to its neu
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br Discussion The patient presented initially only with
2024-04-18
Discussion The patient presented initially only with parietal symptoms in the form of acalculia, visuo-spatial deficits, and visuo-perceptual deficits and dressing apraxia. He also had simultognosia as early symptoms. Later when the disease progressed he had recent memory deficits and language in
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Recent studies demonstrated that AHR has an important role i
2024-04-18
Recent studies demonstrated that AHR has an important role in the interplay between cancer metabolism and tumor-specific immunity. Tryptophan catabolism is increasingly recognized as a metabolic pathway that promotes tumorigenesis through its role in immune suppression [75]. The rate-limiting enzyme
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